{"type":"standard","title":"Efaroxan","displaytitle":"Efaroxan","namespace":{"id":0,"text":""},"wikibase_item":"Q5347187","titles":{"canonical":"Efaroxan","normalized":"Efaroxan","display":"Efaroxan"},"pageid":18485004,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/2/26/Efaroxan.png/330px-Efaroxan.png","width":320,"height":188},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/2/26/Efaroxan.png","width":726,"height":426},"lang":"en","dir":"ltr","revision":"1292606315","tid":"7f1eebf8-3b45-11f0-93e9-46525f2a0725","timestamp":"2025-05-27T21:56:52Z","description":"Chemical compound","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Efaroxan","revisions":"https://en.wikipedia.org/wiki/Efaroxan?action=history","edit":"https://en.wikipedia.org/wiki/Efaroxan?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Efaroxan"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Efaroxan","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Efaroxan","edit":"https://en.m.wikipedia.org/wiki/Efaroxan?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Efaroxan"}},"extract":"Efaroxan is an α2-adrenergic receptor antagonist and antagonist of the imidazoline receptor.","extract_html":"
Efaroxan is an α2-adrenergic receptor antagonist and antagonist of the imidazoline receptor.
"}{"fact":"An adult lion's roar can be heard up to five miles (eight kilometers) away.","length":75}
{"slip": { "id": 133, "advice": "If you find yourself distressed about something, ask yourself if it will still matter tomorrow or next week or next month."}}
{"slip": { "id": 65, "advice": "When having a clear out, ask yourself if an item has any financial, practical or sentimental value. If not, chuck it."}}
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{"type":"standard","title":"Rubicon (protein)","displaytitle":"Rubicon (protein)","namespace":{"id":0,"text":""},"wikibase_item":"Q18034606","titles":{"canonical":"Rubicon_(protein)","normalized":"Rubicon (protein)","display":"Rubicon (protein)"},"pageid":70910894,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/330px-Ideogram_human_chromosome_3.svg.png","width":320,"height":128},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/474px-Ideogram_human_chromosome_3.svg.png","width":474,"height":189},"lang":"en","dir":"ltr","revision":"1240678837","tid":"d038a376-5bfd-11ef-8c91-82c127dd0a57","timestamp":"2024-08-16T18:31:55Z","description":"Human protein involved in autophagy regulation","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Rubicon_(protein)","revisions":"https://en.wikipedia.org/wiki/Rubicon_(protein)?action=history","edit":"https://en.wikipedia.org/wiki/Rubicon_(protein)?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Rubicon_(protein)"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Rubicon_(protein)","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Rubicon_(protein)","edit":"https://en.m.wikipedia.org/wiki/Rubicon_(protein)?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Rubicon_(protein)"}},"extract":"Rubicon is a protein that in humans is encoded by the RUBCN gene. Rubicon is one of the few known negative regulators of autophagy, a cellular process that degrades unnecessary or damaged cellular components. Rubicon is recruited to its sites of action through interaction with the small GTPase Rab7, and impairs the autophagosome-lysosome fusion step of autophagy through inhibition of PI3KC3-C2.","extract_html":"
Rubicon is a protein that in humans is encoded by the RUBCN gene. Rubicon is one of the few known negative regulators of autophagy, a cellular process that degrades unnecessary or damaged cellular components. Rubicon is recruited to its sites of action through interaction with the small GTPase Rab7, and impairs the autophagosome-lysosome fusion step of autophagy through inhibition of PI3KC3-C2.
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